Bertrand Tombal Selected Research

Leuprolide (Lupron)

1/2020	Oral Relugolix for Androgen-Deprivation Therapy in Advanced Prostate Cancer.
11/2017	Clinical Outcomes and Testosterone Levels Following Continuous Androgen Deprivation in Patients with Relapsing or Locally Advanced Prostate Cancer: A Post Hoc Analysis of the ICELAND Study.
12/2014	Disease control outcomes from analysis of pooled individual patient data from five comparative randomised clinical trials of degarelix versus luteinising hormone-releasing hormone agonists.
1/2013	Leuprolide acetate 1-, 3- and 6-monthly depot formulations in androgen deprivation therapy for prostate cancer in nine European countries: evidence review and economic evaluation.
9/2011	A phase III extension trial with a 1-arm crossover from leuprolide to degarelix: comparison of gonadotropin-releasing hormone agonist and antagonist effect on prostate cancer.
7/2010	Changes in alkaline phosphatase levels in patients with prostate cancer receiving degarelix or leuprolide: results from a 12-month, comparative, phase III study.
5/2010	Additional analysis of the secondary end point of biochemical recurrence rate in a phase 3 trial (CS21) comparing degarelix 80 mg versus leuprolide in prostate cancer patients segmented by baseline characteristics.

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Bertrand Tombal Research Topics

Disease

148	Prostatic Neoplasms (Prostate Cancer) 07/2022 - 02/2002
38	Neoplasm Metastasis (Metastasis) 01/2022 - 08/2007
35	Neoplasms (Cancer) 07/2022 - 08/2005
12	Pain (Aches) 07/2022 - 02/2013
11	Disease Progression 11/2021 - 12/2013
5	Fatigue 01/2022 - 07/2013
5	Hypertension (High Blood Pressure) 01/2022 - 07/2013
3	Bone Fractures (Bone Fracture) 07/2022 - 01/2019
3	Urinary Bladder Neoplasms (Bladder Cancer) 12/2016 - 04/2011
2	Kidney Neoplasms (Kidney Cancer) 01/2022 - 12/2013
2	Neutropenia 01/2022 - 01/2022
2	Insulin Resistance 08/2019 - 03/2011
2	Carcinoma (Carcinomatosis) 01/2018 - 12/2016
2	Margins of Excision 02/2017 - 02/2012
2	Bone Diseases (Bone Disease) 01/2017 - 10/2016
2	Cardiovascular Diseases (Cardiovascular Disease) 03/2014 - 03/2011
2	Leukemia 06/2008 - 08/2005
2	Melanoma (Melanoma, Malignant) 06/2008 - 08/2005
1	Febrile Neutropenia 01/2022
1	Diarrhea 10/2021
1	Asthenia 10/2021
1	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2021
1	Second Primary Neoplasms (Neoplasms, Second) 01/2021
1	Chronic Disease (Chronic Diseases) 01/2021
1	Disorders of Excessive Somnolence (Hypersomnia) 01/2021
1	Hypokalemia 08/2019
1	Symptom Flare Up 01/2019
1	Cardiac Arrhythmias (Arrythmia) 01/2019
1	Renal Cell Carcinoma (Grawitz Tumor) 01/2019
1	Myocardial Infarction 01/2019
1	Interstitial Lung Diseases (Interstitial Lung Disease) 01/2019

Drug/Important Bio-Agent (IBA)

39	AndrogensIBA 01/2022 - 05/2006
34	Prostate-Specific Antigen (Semenogelase)IBA 12/2021 - 02/2002
29	enzalutamideIBA 01/2022 - 05/2014
21	Hormones (Hormone)IBA 07/2022 - 06/2008
18	Docetaxel (Taxotere)FDA Link 01/2022 - 11/2008
11	Androgen Receptors (Androgen Receptor)IBA 01/2022 - 07/2013
10	abirateroneIBA 01/2022 - 03/2015
9	Prednisone (Sone)FDA LinkGeneric 01/2022 - 11/2008
9	Testosterone (Sustanon)FDA Link 01/2020 - 10/2008
9	Gonadotropin-Releasing Hormone (GnRH)FDA Link 01/2020 - 07/2007
8	AntigensIBA 01/2022 - 08/2005
8	Radium-223IBA 01/2022 - 12/2018
7	Leuprolide (Lupron)FDA LinkGeneric 01/2020 - 05/2010
6	Denosumab FDA Link 01/2020 - 01/2012
6	Biomarkers (Surrogate Marker)IBA 01/2018 - 07/2005
5	cabazitaxel FDA Link 10/2021 - 09/2013
5	Zoledronic Acid (Zometa)FDA Link 01/2020 - 02/2013
5	acetyl- 2- naphthylalanyl- 3- chlorophenylalanyl- 1- oxohexadecyl- seryl- 4- aminophenylalanyl(hydroorotyl)- 4- aminophenylalanyl(carbamoyl)- leucyl- ILys- prolyl- alaninamide FDA Link 12/2014 - 10/2008
4	Diphosphonates (Bisphosphonates)IBA 09/2018 - 02/2013
4	Pharmaceutical PreparationsIBA 01/2018 - 05/2015
3	darolutamideIBA 07/2022 - 10/2018
3	Abiraterone AcetateIBA 08/2019 - 08/2011
3	Technetium (Technetium 99m)IBA 11/2016 - 08/2007
2	Sunitinib (Sutent)FDA Link 01/2022 - 01/2019
2	Metformin (Glucophage)FDA LinkGeneric 01/2022 - 05/2015
2	LigandsIBA 01/2022 - 10/2018
2	Prednisolone (Predate)FDA LinkGeneric 12/2020 - 01/2019
2	relugolixIBA 11/2020 - 01/2020
2	apalutamideIBA 01/2019 - 03/2015
2	RadiopharmaceuticalsIBA 12/2018 - 02/2013
2	Choline (Choline Chloride)IBA 10/2018 - 01/2017
2	CalciumIBA 09/2018 - 05/2006
2	PlatinumIBA 01/2018 - 04/2011
2	bicalutamide (Casodex)FDA LinkGeneric 11/2017 - 07/2013
2	SeleniumIBA 12/2016 - 03/2012
2	Biological ProductsIBA 03/2015 - 11/2011
2	Monoclonal AntibodiesIBA 10/2013 - 01/2012
2	Dutasteride (Avodart)FDA Link 05/2013 - 06/2012
2	LipidsIBA 03/2011 - 11/2008
2	Proteins (Proteins, Gene)FDA Link 05/2006 - 08/2005
1	TabletsIBA 01/2022
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2022
1	COVID-19 VaccinesIBA 01/2022
1	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 11/2020
1	Complement System Proteins (Complement)IBA 06/2020
1	Therapeutic UsesIBA 01/2020
1	GlucocorticoidsIBA 08/2019
1	MineralocorticoidsIBA 08/2019
1	Insulin (Novolin)FDA Link 08/2019
1	Dexamethasone (Maxidex)FDA LinkGeneric 08/2019
1	DNA (Deoxyribonucleic Acid)IBA 01/2019
1	Alanine Transaminase (SGPT)IBA 01/2019
1	RadiumIBA 01/2019
1	Fluorine-18IBA 12/2018
1	Gallium-68IBA 12/2018

Therapy/Procedure

73	Therapeutics 07/2022 - 08/2007
60	Castration 07/2022 - 06/2008
24	Drug Therapy (Chemotherapy) 01/2022 - 04/2011
18	Prostatectomy (Retropubic Prostatectomy) 01/2020 - 02/2002
15	Radiotherapy 01/2022 - 12/2010
3	Chemoprevention 12/2016 - 01/2011
2	Nephrectomy 01/2022 - 01/2019
2	Precision Medicine 01/2021 - 12/2018
2	Lymph Node Excision (Lymph Node Dissection) 01/2016 - 05/2015
2	Combined Modality Therapy 02/2015 - 10/2011
1	Aftercare (After-Treatment) 01/2022
1	Resistance Training 01/2021
1	Injections 01/2020
1	Palliative Care (Palliative Therapy) 12/2018